Clinical trials are designed to add to medical knowledge and most importantly, the results of these trials can make a difference in the care and treatment of Sjögren’s patients. A clinical trial is important because it contributes to the advancement of science. It provides the participants an opportunity to receive potential benefit from a drug, medical device or procedure or even a lifestyle change such as diet or exercise. The Sjögren’s Foundation is fully committed to the development of new therapeutics that will treat the entire disease, not just one symptom.
Click here to stay up to date on clinical trial and patient recruitment.
The items on this page provide you with:
- Information about participating in clinical trials, including a video
- A State-by-State listing of actively enrolling clinical trials from corporations providing support to the Sjögren’s Foundation
- Other websites listing clinical trials, including easy instruction to navigate the clinicaltrials.gov site.
The following links will provide you with additional knowledge about clinical trials, what's involved and what to expect:
Watch this presentation from our 2022 National Patient Conference. Clinical Trials: What Every Patient Should Know presented by Dr. Herbert Baraf (Accompanying Slides)
- All About Clinical Trials and Sjögren’s
- What to know about Clinical Trials and Sjögren’s
- Clinical Trials 101 (PDF - 106 KB)
- Clinical Trials: Getting Involved (PDF - 104 KB
Below is a listing of active Sjögren’s Clinical trials from companies supporting the Foundation’s mission. These listings are enrolling patients:
This is not an all inclusive list - for additional trials please use the links at the bottom of the page.
Birmingham
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Kelly Nichols
The University of Alabama at Birmingham
University Eye Center
Birmingham, AL 35294
Contact: Alexander Kozuch at (205) 975-3881
Email: ajkoz47 [at] uab [dot] edu (ajkoz47[at]uab[dot]edu)
Click here to learn more
Glendale
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Sherif El-Harazi
Global Research Management/Lugene Eye Institute
1510 S. Central Avenue Suite 300
Glendale, CA 91204
Contact: Logi El-Harazi at (818) 246-2560
Email: logi [at] grmclinical [dot] com (logi[at]grmclinical[dot]com)
Click here to learn more
Los Angeles
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Johnathon Downing
Premier Practice Management/East West Eye Institute, Inc.
420 East Third Street Suite 603
Los Angeles, CA 90013
Contact: Ashley Ku at 323-488-5336
Email: aku [at] ppmmedco [dot] com (aku[at]ppmmedco[dot]com)
Click here to learn more
Newport Beach
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. David Wirta
Eye Research Foundation
520 Superior Avenue Suite 235
Newport Beach, CA 92663
Contact: Yvette Abbascia at 949-650-1863
Email: yvette [dot] abbascia [at] drwirta [dot] com (yvette[dot]abbascia[at]drwirta[dot]com)
Click here to learn more
Rancho Cordova
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Joseph Martel
Martel Eye Medical Group
11216 Trinity River Drive
Rancho Cordova, CA 95670
Contact: Carrie Xiong at (916) 631-7860
Email: carrie [dot] marteleye [at] gmail [dot] com (carrie[dot]marteleye[at]gmail[dot]com)
Click here to learn more
Torrance
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Damien Goldberg
Wolstan & Goldberg Eye Associates
23600 Telo Avenue Suite 100
Torrance, CA 90505
Contact: Jennifer Picone-Jones at (310) 602-5640
Email: tstudy2 [at] wgeye [dot] com (tstudy2[at]wgeye[dot]com)
Click here to learn more
Aurora
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Darren Gregory
University of Colorado Department of Ophthalmology
1675 Aurora Court, 1st Floor Rm 1070
Aurora, CO 80045
Contact: Steve Cho at 720-848-5050
Email: steve [dot] cho [at] ucdenver [dot] edu (steve[dot]cho[at]ucdenver[dot]edu)
Click here to learn more
Colorado Springs
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Blake Simmons
Vision Institute
320 East Fontanero St
Colorado Springs, CO 80907
Contact: Logan Mcconnell at (719) 559-2020 Ext. 116
Email: logan [at] vicolorado [dot] com (logan[at]vicolorado[dot]com)
Click here to learn more
Debary
Sanofi Study #ACT16618
Systemic Sjögren’s Phase 2 Trial
Dr. Kwabena Ayesu
Omega Research
609 N. Charles Richard Beall Blvd
Debary, FL 32713
Contact: Bridgett (386) 668-4202
Email: bthompson [at] omegarcllc [dot] com (bthompson[at]omegarcllc[dot]com)
Click here to learn more
Jacksonville
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Frank Bowden
Bowden Eye & Associates
7205 Bonneval Road
Jacksonville, FL 32256
Contact: Jessica Montgomery at 904-861-3858
Email: jmontgomery [at] bowdeneye [dot] com (jmontgomery[at]bowdeneye[dot]com)
Click here to learn more
Largo
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. P. Lee Shettle
Shettle Eye Research, Inc.
13113 66th Street N.
Largo, FL 33773
Contact: Debbie Shettle at 727-674-2500
Email: debbie [dot] shettle [at] yahoo [dot] com (debbie[dot]shettle[at]yahoo[dot]com)
Click here to learn more
Tampa
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Bernard Perez
Perez Eye Center/International Research Center
4506 Wishart Place
Tampa, FL 33603
Contact: Gelissa Mann at 813-875-6588
Email: gelissa [at] irctampa [dot] com (gelissa[at]irctampa[dot]com)
Click here to learn more
Morrow
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Jennifer Kim
Clayton Eye Clinical Research, LLC
1000 Corporate Center Drive, Suite 120
Morrow, GA, 30260
Contact: Tia Ngo
Phone: 770-968-8888 Ext. 6
Email: tiango [at] claytoneye [dot] net (tiango[at]claytoneye[dot]net)
Click here to learn more
Carmel
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Jennifer Nottage
Midwest Cornea Associates
10300 N. Illinois St. Suite 1020
Carmel, IN 46290
Contact: Chris Bartizal (317-805-4527)
Email: MCAresearch [at] midwesteye [dot] com (MCAresearch[at]midwesteye[dot]com)
Click here to learn more
Bethesda
Blake M Warner, D.D.S
National Institute of Dental and Craniofacial Research
NIH Clinical Center - On the Metro red line (Medical Center stop)
Bethesda, Maryland
STUDY # 20-D-0131
Contact: Sasha Clary
Email: sasha [dot] clary [at] nih [dot] gov (sasha[dot]clary[at]nih[dot]gov)
Phone: (301) 529 -7924
Click here to learn more about Study #20-D-0131
En Español
Boston
Dr. Addy Alt-Holland and Dr. Mabi Singh
Tufts University School of Dental Medicine
1 Kneeland Street
Boston, MA 02111
Study # 00002230
Contact Name: Tiffany Bairos, Lead Coordinator
Phone: (617) 636-2408
Click here for more information
Waltham
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Stephen Foster
Massachusetts Eye Research and Surgery Institution
1440 Main Street Suite 201
Waltham, MA 02451
Contact: Jessica Scott (781) 647-1431 ext. 401 or 402
Email: jscott [at] mersi [dot] com (jscott[at]mersi[dot]com)
Click here to learn more
Winchester
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Jack Greiner
Clinical Eye Research of Boston
955 Main Street, Suite 307
Winchester, MA 01890
Contact: Paula Oliver (781) 729-3008
Email: pjdjoliver [at] msn [dot] com (pjdjoliver[at]msn[dot]com)
Click here to learn more
Kansas City
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Joseph Tauber
Tauber Eye Center
4400 Broadway Suite 202
Kansas City, MO 64111
Contact: Megan Hefter 816-531-9100
Email: mh [at] taubereye [dot] com (mh[at]taubereye[dot]com)
Click here to learn more
St. Louis
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Gregg Berdy
Ophthalmology Associates
12990 Manchester Road, Suite 200
St. Louis, MO 63131
Contact: Dawn Wiemers at (314) 966-3377
Email: dawnwiemers [at] eyecare-partners [dot] com (dawnwiemers[at]eyecare-partners[dot]com)
Click here to learn more
Washington
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Michael Korenfeld
Comprehensive Eye Care
901 East 3rd Street
Washington, MO 63090
Contact: Kara Frohmann 636-390-3999
Email: karaf [at] geccobilling [dot] com (karaf[at]geccobilling[dot]com)
Click here to learn more
New York City
CEQUA Phase 4
Sjögren’s Dry Eye Trial
J. Rocco Robilotto, OD, PhD
Center for Ophthalmic and Vision Research
133 E 54th St., Suite 200
Midtown East, New York, NY 10022
Contact: Alena Koickal
Phone: (212) 650-4888
Email: akoickal [at] ea-ny [dot] com (akoickal[at]ea-ny[dot]com)
Click here to learn more
Asheville
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Jeffrey Schultz
Asheville Eye Associates
8 Medical Park Drive
Asheville, NC 28803
Contact: Amy Moore (828) 258-1586 ext 2505
Email: amoore [at] aea1961 [dot] com (amoore[at]aea1961[dot]com)
Click here to learn more
High Point
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Michael Tepedino
Atrium Health Wake Forest Baptist Ophthalmology Oak Hollow
156 University North Parkway
High Point, NC 27262
Contact: Johanna Brennan at (336) 579-0652
Email: OphthalmologyTrials [at] wakehealth [dot] edu (OphthalmologyTrials[at]wakehealth[dot]edu)
Click here to learn more
Fargo
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Lance Bergstrom
Bergstrom Eye Research
2607 University Drive South
Fargo, ND 58103
Contact: Kayla Geyer at (701) 478-0061
Email: kayla [at] bergstromeye [dot] com (kayla[at]bergstromeye[dot]com)
Click here to learn more
Cleveland
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Marc Abrams
Abrams Eye Center
2322 E. 22nd Street Suite 102
Cleveland, OH 44115
Contact: Peggy Smith (216) 937-2020
Email: psmith213 [at] att [dot] net (psmith213[at]att[dot]net)
Click here to learn more
Cranberry Township
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Christopher Spearman
Scott & Christie Eyecare Associates
105 Brandt Drive Suite 201
Cranberry Township, PA 16066
Contact: Dr. Natasha Hindman (724) 772-3000
Email: nhindman [at] scottandchristie [dot] com (nhindman[at]scottandchristie[dot]com)
Click here to learn more
Rapid City
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Stephen Khachikian, MD
Black Hills Regional Eye Institute
2800 Third Street
Rapid City, SD 57701-7394
Contact: Lizza Teller at (605) 719-3153
Email: lteller [at] bhrei [dot] com (lteller[at]bhrei[dot]com)
Click here to learn more
Nashville
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Melissa Toyos
Toyos Clinic
2204 Crestmoor Road
Nashville, TN 37215
Contact: Sarah Smith (615) 327-4015 ext. 0
Email: ssmith [at] toyosclinic [dot] com (ssmith[at]toyosclinic[dot]com)
Click here to learn more
El Paso
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Lawrence Tafoya
Southwest Eye Institute
4171 North Mesa Street Bldg D, Suite 100
El Paso, TX 79902
Contact: Stacy Morales at 915-545-2333
Email: stacy [dot] morales [at] americanvisionpartners [dot] com (stacy[dot]morales[at]americanvisionpartners[dot]com)
Click here to learn more
Houston
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Stephen Pflugfelder
Alkek Eye Center, Baylor College of Medicine
1977 Butler Blvd
Houston, TX 77030
Contact: Carolyn Smith at (713) 798-7692
Email: carolyn [dot] smith2 [at] bcm [dot] edu (carolyn[dot]smith2[at]bcm[dot]edu)
Click here to learn more
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Nancy Stephens
Advanced Laser Vision & Surgical Institute
Intouch Clinical Research Center
11550 Fuqua Street
Suite #215
Houston, TX 77034
Contact: Teresa Solis: (409) 770-3585
Email: tmsolis [at] intouchcrc [dot] com (tmsolis[at]intouchcrc[dot]com)
Click here to learn more
Falls Church
Sylentis Phase 3 Study# SYL1001_V
Sjögren’s Dry Eye Trial
Dr. Shelly Watson
Northern Virginia Ophthalmology Associates
6565 Arlington Blvd. Suite 250
Falls Church, VA 22042
Contact: Agnes Wingler at (703) 534-3900 option 5
Email: aweyeresearch [at] gmail [dot] com (aweyeresearch[at]gmail[dot]com)
Click here to learn more
Below are additional links that will help you find clinical trials in your area:
The NIH Clinical Research Trials and You website provides general information on participating in clinical research, with a focus on NIH-funded research.
MedlinePlus is a Web-based health information service of the National Library of Medicine.
FDA is responsible for ensuring the safety and effectiveness of drugs, vaccines, and other medical products. Read more about clinical trials and the drug development process on the FDA’s website.
ClinicalTrials.gov is a registry of federally and privately supported clinical trials conducted in the United States and around the world. ClinicalTrials.gov gives you information about a trial's purpose, who may participate, locations, and phone numbers for more details. This information should be used in conjunction with advice from health care professionals. To find trials related to Sjögren's:
Click the link to clinicaltrials.gov
On the LEFT: check the recruiting box to limit to trials actively recruiting THEN click APPLY
On the TOP: click the "on map" tab to see map of US
Click individual states to see available recruiting trials
CenterWatch.com Clinical Trial Listing Service provides patients with unbiased information on clinical trials, with a clinical trial database that contains thousands of currently enrolling trials. Information on drugs and new medical therapies are available to review. CenterWatch also provides patients with health and educational resources about clinical trials and other health information.